"Nerve Function: From Signals to Actions”

Nerves are like wires that transmit signals between your brain and the rest of your body. These signals help you feel things and make you move your muscles.  They control important functions like:

BREATHING

SWALLOWING

DIGESTION

SWEATING

URINATIING AND DEFECATING

Nerve cells are called neurons and are found throughout your body. A lot of neurons are found in the brain and spinal cord.

Nerves, along with your brain and spinal cord, make up your nervous system. When doctors talk about “nerves,” they usually mean the part of your nervous system that is outside of your brain and spinal cord, which is called your peripheral nervous system.

"Nerve Breakdown: Exploring the Danger of Peripheral Neuropathy"

What is Peripheral neuropathy?

Peripheral neuropathy is a condition that develops when the nerves that are located outside of the brain and spinal cord (peripheral nerves) are damaged.

Every nerve in the peripheral system has a specific job. Nerves are divided into:

Sensory nerves that receive sensation like: temperature, pain, vibration and touch.

SENSORY NERVES

Motor nerves that control muscle movement.

MOTOR NERVES

Autonomic nerves that control functions like: blood pressure, sweating, heart rate, digestion, bladder function.

AUTONOMIC NERVES

Symptoms of Peripheral Neuropathy Depend on the Affected Peripheral Nerve

Sensory nerve damage

Unusal Sensation

Pain from light touch

Burning

Numbness

Tingling

Balance problem

Motor nerve damage

Muscle cramping

Twitching

Reflex abnormalities

Autonomic nerve damage

Excessive sweating

Heat intolerance

Getting full quickly

Impotence

Orthostatic hypotension (dizziness or fainting after standing up)

"Nerve Wrath: Unraveling the Culprits of Peripheral Neuropathy”

This is the most common cause. More than half of people with diabetes will develop some type of neuropathy.

DIABETES

These include certain viral or bacterial infections, including Lyme disease, shingles, hepatitis B and C, leprosy, diphtheria, and HIV.

INFECTIONS

These include Sjogren's syndrome, lupus, rheumatoid arthritis, Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy and vasculitis. Also, some cancers related to the body's immune system can cause polyneuropathy. These are a form of autoimmune disorder called paraneoplastic syndrome.

AUTOIMMUNE DISEASES

Disorders such as Charcot-Marie-Tooth disease are hereditary types of neuropathy that run in families.

INHERITED DISORDER

Unhealthy dietary choices made by people with alcoholism, and poor absorption of vitamins can lead to low amounts of essential vitamins in the body.

ALCOHOLISM

Certain medicines, especially chemotherapeutic agents used to treat cancer, can cause peripheral neuropathy.

MEDICINES

Tests to Diagnose Peripheral Neuropathy

Blood tests

To detect many problems, ranging from immune system problems to toxins and poisons, especially metals like mercury or lead.

Electromyogram

To assess the electrical activity of muscles, which can indicate nerve damage

Nerve ultrasound

To detect many problems, ranging from immune system problems to toxins and poisons, especially metals like mercury or lead.

Nerve Conduction Test

To measure the speed and strength of electrical signals in the nerves, helping to determine the type and extent of nerve damage.

Biopsy Test

To assess the density of nerve endings in the skin, which can help diagnose small fiber neuropathy.

Genetic Testing

To identify hereditary causes of neuropathy.

Magnetic Resonance Imaging (MRI)

To identify structural causes of nerve compression, such as herniated discs or tumors.

Disclaimer: The information provided is for general informational purposes only and should not be considered as medical advice. It is important to consult with a qualified healthcare professional or physician to determine the specific tests and treatment options suitable for your type of neuropathy. Each individual’s condition may vary, and a healthcare professional can provide personalized guidance based on your medical history, symptoms, and other relevant factors. Always seek the advice of a physician or other qualified healthcare provider regarding any medical condition or treatment.

Treatment

Wide variety of treatment depending on its cause is available.

Injections, medicines and skin patches.

Medication

Help reconnect cut nerves and relieve pain due to trapped nerves.

Surgery

This can help you recover or improve pain symptoms.

Physical Therapy

Braces, canes and walkers, prescribed footwear and more.

Devices and wearable equipment

Peripheral neuropathy commonly affects your feet. This can cause soft tissue and bone changes, including sores and infections, especially in people with type 2 diabetes.

Podiatry and foot care

Acupuncture, transcutaneous electrical nerve stimulation, injections and surgery to implant a spinal cord stimulator.

References:

  1. https://www.medicalnewstoday.com/articles/317212
  2. https://www.mayoclinic.org/diseases-conditions/peripheral-neuropathy/symptoms-causes/syc-20352061
  3. https://www.frontiersin.org/articles/10.3389/fpain.2023.1162405/full
  4. https://www.valiantlifemedical.com/blog/how-peripheral-neuropathy-can-impact-your-quality-of-life 
  5. https://my.clevelandclinic.org/health/diseases/14737-peripheral-neuropathy
  6. Keltican Product Monograph

Disclaimer: The information provided is for general informational purposes only and should not be considered as medical advice. It is important to consult with a qualified healthcare professional or physician to determine the specific tests and treatment options suitable for your type of neuropathy. Each individual’s condition may vary, and a healthcare professional can provide personalized guidance based on your medical history, symptoms, and other relevant factors. Always seek the advice of a physician or other qualified healthcare provider regarding any medical condition or treatment.